Teriflunomide

What is this medication? 

Teriflunomide, Aubagio
Pyrimidine Synthesis Inhibitor

Indicated for treatment of relapsing multiple sclerosis.

"US Boxed Warning:

Pregnancy/women of childbearing potential:
Teriflunomide is contraindicated in pregnant women or women of childbearing potential who are not using effective contraception. Pregnancy must be excluded prior to initiating treatment in females of reproductive potential."

How does this medication work?

Teriflunomide, Aubagio is an immunomodulatory agent that inhibits pyrimidine synthesis, resulting in antiproliferative and anti-inflammatory effects. It may reduce the number of activated lymphocytes in the CNS.

How should I take this medication? 

Oral: Take 7 mg or 14 mg once daily.

How to Take: Administer without regard to meals.

What should I watch for while using this medication? 

Before starting Teriflunomide, Aubagio make sure your physician is aware of any allergies or medications you currently take, you have hypersensitivity to teriflunomide, leflunomide, or any component of the formulation.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication? 

Alopecia, hypophosphatemia, diarrhea, nausea, lymphocytopenia, increased serum alanine aminotransferase, headache, hypertension, neutropenia, paresthesia, peripheral neuropathy, arthralgia.

Note this is not a complete list of side effects, only common ones.