MULTAQ (Dronedarone)

What is this medication?

MULTAQ (Dronedarone)
Antiarrhythmic, Class III

MULTAQ (Dronedarone) is indicated for prevention and/or management of Paroxysmal or Persistent Atrial Fibrillation.

ALERT: WARNING
MULTAQ (Dronedarone) is conntraindicated in patients with symptomatic heart failure with recent decompensation requiring hospitalization or New York Heart Association (NYHA) class IV heart failure. Dronedarone, Multaq doubles the risk of death in these patients.  Dronedarone, Multaq is contraindicated in patients in atrial fibrillation (AF) who will not or cannot be cardioverted into normal sinus rhythm.

How does this medication work? 

MULTAQ (Dronedarone) is a noniodinated antiarrhythmic agent structurally related to amiodarone exhibiting properties of all 4 antiarrhythmic classes. MULTAQ (Dronedarone) decreases AV conduction and sinus node function through inhibition of calcium channels and beta-receptor blocking activity.

How should I take this medication?

Oral: Take 400mg twice daily with meals.

Note: Administer with morning and evening meal.

What should I watch for while using this medication? 

Before starting MULTAQ (Dronedarone) make sure your physician is aware of any allergies or medications you currently take.  MULTAQ (Dronedarone) can cause a new-onset or worsening of heart failure, acute liver injury, QT prolongation, interstitial lung disease including pulmonary fibrosis and pneumonitis.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Prolonged QT interval, allergic dermatitis, eczema, pruritis, skin rash, diarrhea, nausea, abdominal pain, dyspepsia, vomiting, weakness.

Note this is not a complete list of side effects for MULTAQ (Dronedarone), only common ones.